The paper presents the E-learning project and the work until now done to extend the features of the Italian Remote Laboratory “G.Savastano” to the academic circles of East Europe, Western Balkan and Mediterranean area. In particular, in the framework of the project “Italian-Croatian Remote Laboratory Distributed on Geographic Network”, the Italian-Croatian collaboration is highlighted. The proposed approach follows EU efforts to implement internal Lifelong Learning Program and influence educational systems of EU partner and neighbor Countries while helping them to overcome problems with their own educational systems and lack of resources. Developed experiments give the possibility of achieving practical experience on several fields, while multilingual approach gives the access to such facility to the students coming from different Countries. Moreover, the idea of interactively controlled transfer of knowledge and experience offers a new dimension to the remote experiments enabling them to be executed without supervising necessity.